Immunox for CAR and Freezing Temps

Had a horrible first year last year when I didn’t spray for CAR. Noticed the galls on the Red Cedars starting to open up. most of my apples are green tip to half inch, so I’m guessing I need to spray now. Calling for 33 degrees tonight and 31 tomorrow night. Will spraying Immunox and a sticker with low temps like this hurt the trees? Couldn’t find anything on the labels. But not sure if there is a choice with the damage CAR caused last year. Rainy now, but should clear by 1 pm, and was planning spraying around 4 or 5 pm.