Relatively is the operative word here. Itās oral LD50 in rats ranges somewhere from 1000-10000 LD50 according to Extoxnet. Thatās pretty non-toxic for an organophosphate but that doesnāt tell the whole story. Itās toxic enough it would never fall into the EPA reduced risk certification. Malathion 57 has a āWARNINGā signal word on the label, which is fairly toxic to mammals by EPA standards. WARNING is just one step down from a DANGER/POISON signal word. When an applicator sees WARNING, they know to take a little extra care with the pesticide concentrate. 50% Malathion formulations carry a less severe āCAUTIONā on the label.
Further complicating things is that it takes considerably more active ingredient of Malathion to kill pests. This is significant because many other insecticides may have a more toxic profile in terms of LD50 values of the active ingredient, but take much less active ingredient to kill the pest, which significantly limits the applicator in receiving a harmful dose. As an example, Mustang Maxx I occasionally use (also carries a āWARNINGā signal word on the concentrate) requires only 4 ounces/acre. I spray at 100 gal./acre so thatās 4 ounces of chemical/100 gallons of water.
Malathion 57 is labeled at 32 ounces per acre, 8 times the amount of chemical concentrate vs. Mustang.
However, that doesnāt tell the whole story because Mustang has about 9% active ingredient in the concentrate, while the Malathion I referenced has 6 times the active ingredient in the concentrate (57%). That means while applying I am using about 50 times more active ingredient of malathion vs. Mustang.
Iām not saying I would be afraid to use Malathion (I have used it) but itās not as safe as it might seem when you examine the whole picture.
Iām not trying to be contentious but Iād be interested to see any state organic certifications which allow the use of Malathion. Most of the state certifications use the USDA rules, which would prohibit the use of Malathion. Iāve heard of emergency exemptions for some compounds in organic certification programs, but Iād be surprised if Malathion was ever allowed in a federal or state certified program.
Again, Iāve nothing against Malathion if it works for you (and I think your spray program is clever in that it gets the most out the Malathion) I just donāt want people to come away with the impression that itās as safe as it seems.
Lastly, I wouldnāt say that Malathion, āwill be inactive by the time the bees come outā. Again according to Extoxnet, the half life of Malathion in sunlight is 1.5 days. That means if sprayed at night Malathion will have more than enough potency to kill bees in the morning, if sprayed on blooming weeds. That said, the extremely short half-life in sunlight does make Malathion a more bee friendly choice than a lot of insecticides.
http://extoxnet.orst.edu/pips/malathio.htm