Same, mine was farmland in tobacco country, then suburbs for a few decades before I bought it (and I know for a fact the previous owners were perfectly happy to not only use all kinds of nasty chemicals, they were also perfectly happy to use them against the labeled directions).
I myself grow tobacco, though only the ornamental varieties (I wouldn’t be surprised to find out they have more nicotine though). I also grow a good number of other plants with some pretty nasty insecticides, like chinaberry, torreya, milkweed, and poison ivy (the last one not willingly).
But, as with everything, the dose makes the poison. Nicotine, just like glyphosate and vinegar and organophosphates, has a half life in the soil. After a certain period of time, it breaks down. Sometimes, like with arsenic-based pesticides, the breakdown products are themselves dangerous, but with most stuff that’s not the case.
So it’s a question of exposure. If a field of tobacco gets plowed under, I’d expect the soil there would probably have elevated levels of nicotine, but then again, if the field is plowed under, it’s not like there are going to be many plants in that field blooming anytime soon thereafter. And I suspect a plant covered in dirt leaches more slowly than one that’s chopped up and placed directly in water.
Beyond that, there’s animal behavior. Bees don’t really frequent tobacco much or spend much time in tobacco fields, it’s moth pollinated after all. But white clover? Yeah. And if, unknown to the bees, said white clover got doused with tobacco extract the day before? Yeah, dead bees.
One or two people spraying orchards with tobacco probably isn’t going to matter one way or another. But if large numbers of people, especially people who otherwise attract large numbers of pollinators to their land, start poisoning their flowers with organic but toxic sprays, it’ll make a difference, and not in a good way.
Again, people should use caution, regardless of if they bought a poison or made it themselves. It’s the dose that makes the poison, not the label calling it “organic” or not. Spraying has a role to play in a well-managed garden, but as with all tools, it’s one that should be managed carefully and thoughtfully.