Some folks use garlic and hot pepper sprays very few use tobacco, some use chrysanthemum.
A friend of a friend that was a hort professor at WKU uses tobacco tea on his orchards and the pictures that i seen everything looks immaculate… even the deer do not browse he reports. I havent tried it myself but i think eventually i will.
Im trying to build up my predators and natural defenses first before i decide on what is best for my location…so i dont spray anything.
Edible Landscaping talks about a collar of tobacco around some things to prevent borers… not sure if that is proven or why he talks about it.
Some interesting discussion here (YMMV).